Clinical Research Program Underway To Validate Potential of
Laboratory studies show that toothpastes containing zinc or stannous and mouthwash formulas with cetylpyridinium chloride (CPC) neutralize the virus that causes COVID-19 by 99.9 percent. The studies are part of a Colgate research program that includes clinical studies among infected people to assess the efficacy of oral care products in reducing the amount of the virus in the mouth, potentially slowing the transmission of the COVID-19 virus.
In the laboratory studies — the first to include toothpaste — Colgate Total and Meridol toothpastes neutralized 99.9% of the virus after two minutes of contact.
The results suggest that some toothpastes and mouthwashes may help reduce the spread of SARS-CoV-2, the virus that causes COVID-19, by temporarily reducing the amount of virus in the mouth. The virus spreads through respiratory droplets or small particles produced when an infected person coughs, sneezes, sings, talks, or breathes, according to the
“We’re at the early stages of our clinical investigations, but our preliminary laboratory and clinical results are very promising,” said Dr.
Concurrent to the laboratory study, Colgate sponsored a clinical study involving some 50 hospitalized subjects with COVID-19. This study demonstrated the ability of Colgate Total (with CPC and zinc), Colgate Peroxyl, and Colgate PerioGard mouthwashes to substantially reduce the amount of the virus in the mouth temporarily. The researchers plan to share their findings in December. Additional Colgate-supported clinical research studies on toothpaste and mouthwashes are in early stages at
“Colgate is collaborating with numerous investigators throughout the globe to conduct clinical research to explore the potential of oral care products to reduce oral viral loads as a risk reduction strategy,”
As the world’s #1 trusted dental expert, Colgate is committed to leading in science and to ensuring that its products address health challenges and meet consumers’ needs. For more information about the effects of oral hygiene on overall health and additional insights on mask mouth and other topics, visit www.colgate.com.